Dr. Alexandra Weyrich


Head of Wildlife Epigenetics

Department of Evolutionary Genetics


Tel: 0049 (0) 30 5168 - 313
Research interests

- Epigenetic mechanims and regulation of gene expression

- Epigenetics of social systems

- Environmental factors

- Thermoregulation

Selected publications


Guerrero TP,  Fickel J,  Benhaiem S, Weyrich  A (2020): Epigenomics and gene regulation in mammalian social systems. CURR ZOOL, 66, 307–319.
Wahedi A, Günther A, Weyrich A, Sondheimer N (2020): The mitochondrial genome of Cavia aperea, MITOCHOND DNA Part B, Resources, accepted.
Weyrich A,Yasar S, Lenz D, Fickel J (2020): Tissue‑specific epigenetic inheritance after paternal heat exposure in male wild guinea pigs. MAMM GENOME Epub ahead of print.
Al-khlifeh E, Balard A, Jarquín-Díaz VH, Weyrich A, Wibbelt G, Heitlinger E(2019): Eimeria falciformis BayerHaberkorn1970 and novel wild derived isolates from house mice: differences in parasite lifecycle, pathogenicity and host immune reactions. BioRxiv, pre-print.
Somerville V, Schwaiger M, Hirsch PE, Walser J-C, Bussmann K, Gebhardt I C, Weyrich A, Burkhardt-Holm P, Adrian-Kalchhauser I (2019): DNA methylation patterns in the round goby hypothalamus support an on-the-spot decision scenario for territorial behaviour. GENES- Special Issue on Epigenetics and Adaptation, GENES 10(3), 219
Weyrich A, Lenz D, Fickel J (2019): Environmental change-dependent transgenerational epigenetic response. GENES 10(1), 4.
Weyrich A, Jeschek M, Schrapers KT, Lenz D, Chung H, Rübensam K, Yasar S, Schneemann M, Ortman S, Jewgenow K, Fickel J (2018): Diet changes alter paternally inherited epigenetic pattern in male wild guinea pigs. ENVIRON EPIG 4(2): dvy011.
Weyrich A, Benz S, Karl S, Jeschek M, Jewgenow K, Fickel J (2016): Paternal heat exposure causes DNA methylation and gene expression changes of Stat3 in wild guinea pig sons. ECOL EVOL 6(9): 2657-2666;
Weyrich A, Lenz D, Jeschek M, Chung TH, Rübensam K, Göritz K, Jewgenow K, Fickel J (2016): Paternal intergenerational epigenetic response to heat exposure in male wild guinea pigs. MOL ECOL 25 (8): 1729-1740 – special issue Epigenetic Studies in Ecology and Evolution.
Weyrich A, Schüllermann T, Heeger F, Jeschek M, Mazzoni C.J., Chen W, Schumann K, Fickel J (2014): Whole genome sequencing and methylome analysis of the wild guinea pig. BMC GENOMICS 15(1):1036.
Hennig W, Weyrich A (2013): Histone modifications in the male germ line of Drosophila; BMC DEV BIOL 13:7.
Kärst S, Strucken EM, Schmitt AO, Weyrich A, de Villena FPM, Hyuna Yang, Brockmann GA (2013): Effect of the myostatin locus on muscle mass and intramuscular fat content in a cross between mouse lines selected for hypermuscularity. BMC GENOMICS 14:16.
Weyrich A (2012): Preparartion of genomic DNA from mamalian sperm. Current Protocols of Molecular Biology, Chapter: Unit 2.12.1-3, Taylor G (ed), Wiley-Blackwell, Pagosa Springs, USA.
Fickel J, Weyrich A (2010); Female mate choisce in rodents. In: Kaoru Hashimoto: From gene to animal behavior, Sprnger Verlag (Japan) 4 (19), ISBN 978-4-431-53892-9
Weyrich A, Axtner J, Sommer S (2010): Selection and validation of reference genes for real-time RT-PCR studies in the non-model species Delomys sublineatus, an Brazilian rodent. BIOCHEM BIOPHYS RES COMMUN 392(2): 145-149.
Weyrich A, Mahr JA, Jauernig O, Göritz F, Fritzenkötter A, Blottner S, Fickel J (2010): Seasonal changes of gene expression in roe deer (Capreolus capreolus) testis measured by  expression microarray analysis. Trend in Animal and Veterinary Sciences Journal 1 (2): 49-64.
Weyrich A, Tang X, Xu G, Schrattenholz A, Hunzinger C, Hennig W (2008): Mammalian DNMTs in the male germ line DNA of Drosophila. BIOCHEM CELL BIOL. 86(5): 380-385.
Last updated on June, 3 2020.